pentobarbital will reduce the extent or result of diazepam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Sturdy or reasonable CYP3A4 inducers may possibly boost charge of diazepam elimination; for that reason, efficacy of diazepam could possibly be reduced.
pentobarbital will minimize the level or impact of eletriptan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital increases toxicity of ifosfamide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. CYP3A4 inducers may perhaps improve the metabolism of ifosfamide to its Lively alkylating metabolites.
pentobarbital will reduce the level or effect of vardenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Administer barbiturates with warning in people with hepatic injury and at decreased doses originally; barbiturates really should not be administered to individuals exhibiting the premonitory indications of hepatic coma
pentobarbital will lessen the extent or result of darunavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will minimize the level or effect of oxybutynin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unfamiliar.
pentobarbital will reduce the extent or outcome of click here maraviroc by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will decrease the extent or result of stiripentol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. If not able to avoid coadministration of stiripentol with robust CYP3A4 inducers, enhance stiripentol dose.
pentobarbital will decrease the level or influence of estradiol vaginal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will minimize the extent or result of terbinafine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
buprenorphine subdermal implant and pentobarbital equally boost sedation. Stay away from or Use Alternate Drug. Restrict use to individuals for whom choice treatment possibilities are inadequate
Parenteral solutions of barbiturates are remarkably alkaline; Serious care should be taken to stay away from perivascular extravasation or intra-arterial injection; extravascular injection might bring about area tissue injury with subsequent necrosis; implications of intra-arterial injection could change from transient soreness to gangrene from the limb; any complaint of ache within the limb warrants stopping the injection
pentobarbital will lessen the extent or result of zaleplon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Mysterious.